Characterization of Viral Insulin-Like Peptides Reveals Unique White Adipose Tissue Specific Characteristics
نویسندگان
چکیده
منابع مشابه
Anterograde transneuronal viral tract tracing reveals central sensory circuits from white adipose tissue.
The origins of the sympathetic nervous system (SNS) innervation of white adipose tissue (WAT) have been defined using the transneuronal viral retrograde tract tracer, pseudorabies virus. Activation of this SNS innervation is acknowledged as the principal initiator of WAT lipolysis. The central control of WAT lipolysis may require neural feedback to a brain-SNS-WAT circuit via WAT afferents. Ind...
متن کاملWhite Adipose Tissue Resilience to Insulin Deprivation and Replacement
INTRODUCTION Adipocyte size and body fat distribution are strongly linked to the metabolic complications of obesity. The aim of the present study was to test the plasticity of white adipose tissue in response to insulin deprivation and replacement. We have characterized the changes of adipose cell size repartition and gene expressions in type 1 diabetes Sprague-Dawley rats and type 1 diabetic s...
متن کاملAdipose tissue ELVs induce insulin resistance Adipose tissue exosome-like vesicles mediate activation of macrophage- induced insulin resistance A running title: Adipose tissue ELVs induce insulin resistance
Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35294 Department of Nutrition, University of Alabama at Birmingham, Birmingham, AL 35294 ...
متن کاملMolecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides
Multicellular animals match costly activities, such as growth and reproduction, to the environment through nutrient-sensing pathways. The insulin/IGF signaling (IIS) pathway plays key roles in growth, metabolism, stress resistance, reproduction, and longevity in diverse organisms including mammals. Invertebrate genomes often contain multiple genes encoding insulin-like ligands, including seven ...
متن کاملCIDE Family-Mediated Unique Lipid Droplet Morphology in White Adipose Tissue and Brown Adipose Tissue Determines the Adipocyte Energy Metabolism
White adipose tissue (WAT) stores energy as triacylglycerol in preparation for fasting state. In contrast, brown adipose tissue (BAT) consumes energy and produces heat in a cold environment. One of the major differences between these two adipose tissues is the morphology of the intracellular lipid droplet (LD), which is large and unilocular in WAT and small and multilocular in BAT. Although the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the Endocrine Society
سال: 2021
ISSN: 2472-1972
DOI: 10.1210/jendso/bvab048.892